Infertility: RPL Testing

After our third miscarriage I was finally diagnosed with recurrent pregnancy loss. I knew this was coming, I just felt it after our second miscarriage. As much as doctors try to normalize two consecutive miscarriages it’s not normal, at least not in my opinion.

After our OBGYN telling us we were going to miscarry our third baby via telephone, they asked us to come in the following week for a follow-up ultrasound, labs and discussion. As much as I didn’t want to go I knew I needed to to get some answers, hopefully.

Jon and I took the afternoon and headed to the office. They again allowed Jon in for the ultrasound but nothing else. They confirmed what we had expected, I passed the baby over the weekend. It was true, this nightmare was real. As much as I knew what was going to happen, one always holds out this tiniest bit of hope that this isn’t real. After the ultrasound I waited what seemed like forever to be seen by the OBGYN. When she finally came in she said the three words I knew were coming – recurrent pregnancy loss. I asked her why, I wanted to know why this kept happening to us. She told me there are four common reasons for RPL:

  1. Chromosomal Issues
    • Before we left California for Nevada we had our Karyotype testing done. That came back completely normal. So we know for a fact that neither Jon or myself have any chromosomal abnormalities that would cause a miscarriage.
  2. Uterine Abnormalities
    • This shouldn’t be an issue because I’ve had several ultrasounds and my HSG tests (you can read more about them here and here) came back normal. I know there is additional testing that can be done as well such as a saline ultrasound, MRI and hysteroscopy but I just don’t in my heart of hearts feel this is the issue. We are open to additional testing however.
  3. Blood Clotting Disorders (Antiphospholipid Antibodies, MTHFR)
    • We have never been tested for any of these.
  4. Hormone Issues (Thyroid, A1C, Prolactin, Ovarian Reserve)
    • I’ve been tested and all came back normal however by Thyroid was on the very borderline.

So she suggested that our next steps be to check for Antiphospholipid antibodies and recheck for thyroid and A1C issues.

I have to wait six weeks before testing due to false positives that maybe found right after pregnancy loss. Let’s hope that the answer is as simple as one of these issues so that we can move forward with a viable pregnancy.


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